The treble-winners are unbeaten in their last eight in all competitions, including five wins, while they have eight wins from nine home games in all competitions this season. Spurs have lost to Chelsea, Wolves and Aston Villa in recent weeks and City present an even tougher test. Ange Postecoglou will be without 10 senior players for the trip to Manchester including the likes of first-choice central-defensive pairing Cristain Romero and Micky van de Ven as well as midfielders James Maddison, Yves Bissouma and Rodrigo Betancur.
The Etihad Stadium is the last place Spurs will want to visit after a run of three consecutive defeats and with a number of key players missing. Manchester City vs Tottenham bet-builder tips Bet-builder tip 1: Man City to win Already used the Betfred sign-up offer? Check out all the latest bookmaker offers and the best betting sites.